Ignite Creation Date:
2025-12-24 @ 4:45 PM
Ignite Modification Date:
2026-05-15 @ 7:28 AM
Study NCT ID:
NCT04470050
Status:
COMPLETED
Last Update Posted:
2023-10-26
First Post:
2020-07-01
Is Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal
Sponsor:
BioXcel Therapeutics Inc
Organization:
Conditions & Keywords Data
Conditions:
Conditions
| Condition Brief | Condition Text | View |
|---|---|---|
| None | Opioid Withdrawal | View |
Keywords:
Keywords
| Keyword Brief | Keyword Text | View |
|---|---|---|
| None | Opioid | View |
| None | Opioid Addiction | View |
| None | Opioid Dependance | View |
| None | Opioid Withdrawal Symptoms | View |
| None | Opioid Withdrawal Syndrome | View |
| None | Morphine Addiction | View |
| None | delta-opioid receptors | View |
| None | Inhibition of nociceptive afferent neurons (PNS System) | View |
| None | Reduction of nociceptive transmission | View |
| None | Activation of descending inhibitory pathways (CNS System) | View |
| None | Analgesic Opioids | View |
| None | Drug craving | View |
| None | μ-δ-opioid (Mu-Delta) receptor | View |
| None | μ-binding (Mu receptors) | View |
| None | afferents within laminae I and II | View |
| None | κ-opioid receptor (KOR) | View |
| None | δ-opioid receptor (DOR) agonist | View |
| None | (+)-pentazocine | View |
| None | σ receptor antagonists | View |
| None | Downstream involvement of the σ receptor | View |
| None | Increase phosphorylation in p38 MAPK | View |
| None | IL-10 | View |
| None | Activation of IL-12 | View |
| None | IL-12 increase in T-cell immune response | View |
| None | pentacyclic 3°amine (alkaloid) | View |
| None | stereogenic centers | View |
| None | tetrahydroisoquinoline reticuline | View |
| None | CPY2D6 | View |
| None | benzylisoquinoline alkaloid | View |
| None | p38 MAPK-dependent pathway | View |
| None | kappa-opioid receptors | View |
| None | Short Opiate Withdrawal Scale (SOWS)-Gossop | View |
| None | Clinical Opiate Withdrawal Scale (COWS) | View |
| None | Agitation and Calmness Evaluation Scale (ACES) | View |
| None | Discontinuation of Morphine Maintenance | View |