Ignite Creation Date:
2025-12-25 @ 3:54 AM
Ignite Modification Date:
2026-07-23 @ 9:54 PM
Study NCT ID:
NCT03426202
Status:
UNKNOWN
Last Update Posted:
2019-06-17
First Post:
2018-02-01
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Effect of Modafinil on Affective and Cognitive Processing
Sponsor:
University of Electronic Science and Technology of China
Organization:
Study Overview
Official Title:
The Effect of Modafinil on Neural Processing During the Interference and Feedback Based Learning Task
Status:
UNKNOWN
Status Verified Date:
2019-06
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The study aims to examine whether a single dose of modafinil (200mg, p.o.) can affect feedback-based learning and interference processing in healthy male subjects.
Detailed Description:
Based on previous animal and human research suggesting a catecholamine-mediated, potentially pro-cognitive, mechanism of action of modafinil, the present study seeks to explore effects of modafinil on feedback-based learning and interference processing in healthy subjects. To this end, the present randomized double-blind, between-subject, placebo-controlled pharmaco-fMRI experiment plans to determine the behavioral and neural effects of a single dose of p.o.modafinil (200mg) versus placebo on validated feedback-based learning and emotional/non-emotional cognitive conflict paradigms. To control for potential effects of pre-medication personality traits as well as effects of modafinil on subjective task performance, subjects will be administered pre-treatment assessing relevant personality traits and post-treatment assessments of meta-cognitive confidence estimation.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: