Compound Report Overview
Compound Name:
MAPROTILINE
Compound Identifier:
706490
Mol Structure 2D:
706490
Molecular Weight:
277
Formula:
C20 H23 N
Development Status:
US FDA Approved
SMILES:
CNCCCC1(CCC2c3ccccc31)c4ccccc24
Compound Literature
| Compound | Gene Type | Activity | Description | View |
|---|---|---|---|---|
| MAPROTILINE | Ki | 20.8 | inhibits, uptake ([3H]dopamine), rat striatum homogenates, inhibition of synaptosomal uptake of tritiated monoamines | View |
| MAPROTILINE | Ki | 7.9 | inhibits, uptake ([3H]5-hydroxytryptamine), rat hypothalamus homogenates, inhibition of synaptosomal uptake of tritiated monoamines | View |
| MAPROTILINE | Ki | 5.91 | inhibits, uptake ([3H]5-hydroxytryptamine), rat hippocampus homogenates, inhibition of synaptosomal uptake of tritiated monoamines | View |
| MAPROTILINE | Ki | 4.87 | inhibits, uptake ([3H]5-hydroxytryptamine), rat cortex homogenates, inhibition of synaptosomal uptake of tritiated monoamines | View |
| MAPROTILINE | Ki | .00197 | inhibits, uptake ([3H]noradrenaline), rat hypothalamus homogenates, inhibition of synaptosomal uptake of tritiated monoamines | View |
| MAPROTILINE | Ki | .00115 | inhibits, uptake ([3H]noradrenaline), rat cortex homogenates, inhibition of synaptosomal uptake of tritiated monoamines | View |
| MAPROTILINE | Kd | .0111 | inhibit, binding ([3H]nisoxetine), rat brain synaptosomes | View |