Gene:
misshapen-like kinase 1 (zebrafish)
Gene ID:
197855
Symbol:
MINK1
Species:
1000
Description:
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified.