Gene:
oligophrenin 1
Gene ID:
198539
Symbol:
OPHN1
Species:
1000
Description:
Oligophrenin 1 has 25 exons and encodes a Rho-GTPase-activating protein. The Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for non-specific X-linked mental retardation.