Gene:
a disintegrin and metalloproteinase domain 19 (meltrin beta)
Gene ID:
198824
Symbol:
ADAM19
Species:
1000
Description:
This gene encodes a disintegrin and metalloprotease (ADAM) domain 19, which is a member of the ADAM protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing generates 2 transcript variants for this gene.