Gene:
glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease)
Gene ID:
198834
Symbol:
G6PC
Species:
1000
Description:
Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease).