Gene:
euchromatic histone methyltransferase 1
Gene ID:
205132
Symbol:
EHMT1
Species:
1000
Description:
Histone methyltransferase. Methylates Lys-9 of histone H3 (in vitro). H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle.