Gene:
aldehyde dehydrogenase 1 family, member L1
Gene ID:
198934
Symbol:
ALDH1L1
Species:
1000
Description:
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.