Gene:
protease, serine, 3 (mesotrypsin)
Description:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Additional transcript variants for this gene have been described, but their full length sequences have not been determined.