Gene:
PR/SET domain containing protein 8
Gene ID:
199425
Symbol:
Species:
1000
Description:
Histone methyltransferase. Methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. Nucleosomes are preferred as substrate compared to free histones. May play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail.