Gene:
myeloid cell leukemia sequence 1 (BCL2-related)
Gene ID:
199480
Symbol:
MCL1
Species:
1000
Description:
The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.