Gene:
CD58 antigen, (lymphocyte function-associated antigen 3)
Gene ID:
199585
Symbol:
CD58
Species:
1000
Description:
Ligand of the T lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T lymphocytes with target cells and antigen- presenting cells and the T lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.