Gene:
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
Gene ID:
199898
Symbol:
TCF3
Species:
1000
Description:
Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.