Gene:
nei endonuclease VIII-like 3 (E. coli)
Gene ID:
200396
Symbol:
NEIL3
Species:
1000
Description:
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002).[supplied by OMIM]