Gene:
cubilin (intrinsic factor-cobalamin receptor)
Gene ID:
200404
Symbol:
CUBN
Species:
1000
Description:
Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia.