Gene:
phospholipase C, delta 3
Description:
PLCD3 belongs to a large family of enzymes that catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate the second messengers Ins(1,4,5)P3 and diacylglycerol, which mediate a wide variety of cellular stimuli.[supplied by OMIM]