Gene:
Nuclear protein localization 4
Gene ID:
200462
Symbol:
Species:
1000
Description:
The ternary complex containing UFD1L, VCP and NPL4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPL4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity).