Gene:
prefoldin 5
Gene ID:
200481
Symbol:
PFDN5
Species:
1000
Description:
Prefoldin is a heterohexameric chaperone protein which assists in the correct folding of other proteins. It binds specifically to cytosolic chaperonin and transfers target proteins. Prefoldin may function by selectively targeting nascent actin and tubulin chains pending their transfer to cytosolic chaperonin for final folding and/or assembly. It promotes folding in an environment in which there are many competing pathways for nonnative proteins. This gene encodes a subunit of prefoldin, prefoldin 5. This subunit is associated with c-myc and is thought to repress the transcriptional activity of c-myc.