Gene:
GDNF family receptor alpha 4
Description:
The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.