Gene:
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
Gene ID:
200586
Symbol:
HADHB
Species:
1000
Description:
The HADHA (MIM 600890) and HADHB genes encode the alpha and beta subunits of the mitochondrial trifunctional protein, respectively. The heterocomplex contains 4 alpha and 4 beta subunits and catalyzes 3 steps in the beta-oxidation of fatty acids, including the long-chain 3-hydroxyl-CoA dehydrogenase step. The beta subunit harbors the 3-ketoacyl-CoA thiolase activity (Kamijo et al., 1994).[supplied by OMIM]