Gene:
pleckstrin homology-like domain, family A, member 1
Gene ID:
200657
Symbol:
PHLDA1
Species:
1000
Description:
Pleckstrin homology domains bind polyphosphoinositides and are involved in platelet cytoskeletal changes. This gene contains a (CAG)n trinucleotide repeat which has been associated with several neurological disorders in which the repeats code for polyglutamine in the protein. This gene may play an important role in the anti-apoptotic effects of insulin-like growth factor I.