Gene:
POU domain, class 2, associating factor 1
Gene ID:
200673
Symbol:
POU2AF1
Species:
1000
Description:
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. Its boost the OCT-1 mediated promoter activity and to a lesser extent, that of OCT-2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B cells to antigens and required for the formation of germinal centers.