Gene:
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
Gene ID:
201121
Symbol:
TLE2
Species:
1000
Description:
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).