Gene:
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
Gene ID:
201215
Symbol:
TAF1A
Species:
1000
Description:
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.