Gene:
wingless-type MMTV integration site family, member 8A
Gene ID:
201723
Symbol:
WNT8A
Species:
1000
Description:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. It encodes a protein which shows 81% amino acid identity to the mouse Wnt8A protein. Among members of the human WNT family, this protein is most similar to WNT8B protein (64% total amino acid identity). Alternative splicing of this gene generates two transcript variants.