Gene:
SEC6-like 1 (S. cerevisiae)
Gene ID:
202696
Symbol:
SEC6L1
Species:
1000
Description:
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the v-ral simian leukemia viral oncogene homolog A (RALA), a Ras-related small GTPase involved in controlling actin cytoskeletal remodeling and vesicle transport. The protein complex containing the similar protein in rat was reported to be involved in synaptic vesicle docking and fusion at the presynaptic terminal.