Gene:
voltage-dependent anion channel 1
Gene ID:
202875
Symbol:
VDAC1
Species:
1000
Description:
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.