Gene:
nudix (nucleoside diphosphate linked moiety X)-type motif 3
Gene ID:
202998
Symbol:
NUDT3
Species:
1000
Description:
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998).[supplied by OMIM]