Gene:
CDK5 regulatory subunit associated protein 3
Gene ID:
203108
Symbol:
CDK5RAP3
Species:
1000
Description:
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation. Three transcript variants encoding two different isoforms have been found for this gene.