Gene:
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
Gene ID:
203263
Symbol:
SGCG
Species:
1000
Description:
Gamma-sarcoglycan is one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin, probably to provide a link between the membrane associated cytoskeleton and the extracellular matrix. Defects in the protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C).