Gene:
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
Gene ID:
193968
Symbol:
SLC25A21
Species:
1000
Description:
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM]