Gene:
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
Gene ID:
209743
Symbol:
HCN2
Species:
1000
Description:
Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity).