Gene:
mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)
Gene ID:
209690
Symbol:
MED8
Species:
1000
Description:
This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Five alternative transcripts encoding four isoforms have been described.