Gene:
hairy and enhancer of split 6 (Drosophila)
Gene ID:
209683
Symbol:
HES6
Species:
1000
Description:
Does not bind DNA itself but suppresses both HES1- mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to up-regulate transcription in its presence. Promotes cell differentation (By similarity).