Gene:
lysyl oxidase-like 2
Gene ID:
209488
Symbol:
LOXL2
Species:
1000
Description:
LOXL2 is a member of the lysyl oxidase (LO; MIM 153455) gene family. LO is an extracellular, copper-dependent enzyme that initiates the cross-linking of collagens and elastin by catalyzing the oxidative deamination of peptidyl lysine to alpha-aminoadipic-delta-semialdehyde. Members of the LO family have diverse functions, including tumor suppression and cell adhesion and senescence.[supplied by OMIM]