Gene:
msh homeo box homolog 2 (Drosophila)
Gene ID:
209276
Symbol:
MSX2
Species:
1000
Description:
Mutations in this gene are associated with craniosynostosis and enlarged parietal foramina. Wildtype levels of this gene activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. This protein promotes cell growth under certain conditions and may be an important target for the RAS signaling pathways.