Gene:
folate receptor 3 (gamma)
Gene ID:
203759
Symbol:
FOLR3
Species:
1000
Description:
The protein encoded by this gene is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein is constitutively secreted in hematopoietic tissues and is a potential serum marker for certain hematopoietic malignancies. This protein has a 71% and 79% sequence homology with the FOLR1 and FOLR2 proteins, respectively.