Gene:
molybdenum cofactor synthesis 1
Gene ID:
208958
Symbol:
MOCS1
Species:
1000
Description:
Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in molybdenum cofactor biosynthesis. This gene produces a bicistronic mRNA that has the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the bicistronic mRNA. Three splice variants have been found for this gene, two of which are monocistronic and express proteins (MOCS1A-MOCS1B) that result from a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A.