Gene:
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
Gene ID:
208837
Symbol:
ST8SIA4
Species:
1000
Description:
The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.