Gene:
glutamate receptor, ionotropic, kainate 1
Gene ID:
208249
Symbol:
GRIK1
Species:
1000
Description:
This gene encodes one of the many ionotropic glutamate receptor (GluR) subunits that function as ligand-gate ionic channels. The specific GluR subunit encoded by this gene is of the kainate receptor subtype. Receptor assembly and intracellular trafficking of ionotropic glutamate receptors are regulated by RNA editing and alternative splicing. These receptors mediate excitatory neurotransmission and are critical for normal synaptic function. Two alternatively spliced transcript variants that encode different isoforms have been described. Exons of this gene are interspersed with exons from the C21orf41 gene, which is transcribed in the same orientation as this gene but does not seem to encode a protein.