Gene:
tumor necrosis factor receptor superfamily, member 10a
Gene ID:
208248
Symbol:
TNFRSF10A
Species:
1000
Description:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.