Gene:
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Gene ID:
207936
Symbol:
CDKN1C
Species:
1000
Description:
Cyclin-dependent kinase inhibitor 1C is a tight-binding inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations of CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome suggesting that it is a tumor suppressor candidate.