Gene:
transcription elongation factor B polypeptide 3B (elongin A2)
Gene ID:
207760
Symbol:
TCEB3B
Species:
1000
Description:
This gene encodes the protein elongin A2, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and it is capable of forming a stable complex with elongins B and C.