Gene:
N-acetylglucosamine-1-phosphotransferase, gamma subunit
Gene ID:
207060
Symbol:
GNPTG
Species:
1000
Description:
UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-phosphotransferase) catalyzes the initial step in the synthesis of the mannose 6-phosphate determinant required for efficient intracellular targeting of newly synthesized lysosomal hydrolases to the lysosome. GlcNAc-phosphotransferase is an alpha-2/beta-2/gamma-2 hexameric complex. Also see GNPTA (MIM 607840).[supplied by OMIM]