Gene:
adrenergic, alpha-1A-, receptor
Gene ID:
191153
Symbol:
ADRA1A
Species:
1000
Description:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates 4 transcript variants, which encode 4 different isoforms with distinct C termini but having similar ligand binding properties.