Gene:
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
Description:
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.