Gene:
inhibitor of Bruton agammaglobulinemia tyrosine kinase
Gene ID:
191284
Symbol:
IBTK
Species:
1000
Description:
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.