Gene:
phosphoribosyl pyrophosphate synthetase 1-like 1
Description:
This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits for phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. Studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon.