Gene:
SMAD, mothers against DPP homolog 4 (Drosophila)
Gene ID:
191542
Symbol:
SMAD4
Species:
1000
Description:
Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor.